- Title
- Proposed empiric antibiotic therapy for prosthetic joint infections: an analysis of the Prosthetic Joint Infection in Australia and New Zealand, Observational (PIANO) cohort
- Creator
- Davis, Joshua S.; Metcalf, Sarah; Paterson, David L.; Robinson, James O.; Clarke, Benjamin; Manning, Laurens
- Relation
- Internal Medicine Journal Vol. 52, Issue 2, p. 322-325
- Publisher Link
- http://dx.doi.org/10.1111/imj.15677
- Publisher
- John Wiley & Sons
- Resource Type
- journal article
- Date
- 2022
- Description
- Empiric antibiotic therapy in suspected prosthetic joint infection should cover likely pathogens while avoiding overly broad-spectrum antibiotics. We analysed individual patient data from a large prospective cohort study (Prosthetic Joint Infection in Australia and New Zealand, Observational (PIANO)) and found that causative organisms vary with the presentation type, with early post-operative infections more likely to be polymicrobial (41%) compared with late acute infections (10%). We thus propose empirical regimens tailored to the presentation type and presence or absence of sepsis.
- Subject
- prosthetic joint infection; empirical antibiotics; septic arthritis; infections
- Identifier
- http://hdl.handle.net/1959.13/1472843
- Identifier
- uon:48933
- Identifier
- ISSN:1444-0903
- Language
- eng
- Reviewed
- Hits: 555
- Visitors: 555
- Downloads: 0